Back in 2001, after the first tech bubble burst, Seth Godin wrote:

Here’s a question that you should clip out and tape to your bathroom mirror. It might save you some angst 15 years from now. The question is, What did you do back when interest rates were at their lowest in 50 years, crime was close to zero, great employees were looking for good jobs, computers made product development and marketing easier than ever, and there was almost no competition for good news about great ideas?

He just resurfaced this now and argues it holds true today.

Quick thoughts on how to take advantage of this:

• Learn to program. It isn’t that hard.
• Borrow now. Interest rates will probably be higher in 5-10 years, since they can’t go much lower.
• Change jobs, unless you love what you’re doing.
• Learn how to market things.

Personally, programming/marketing are the top areas I want to immerse myself in for the next year. Outside of work, at least.